Hereditary spastic paraplegia (HSP) is a group of conditions that make it hard for a person to move their legs. It’s something a kid is born with and it gets worse as they grow up. HSP can make a kid’s leg muscles stiff and weak, so walking is tricky.
How common is Hereditary Spastic Paraplegia?
HSP is a rare condition, affecting about 20,000 people in the United States.
What are some symptoms of Hereditary Spastic Paraplegia?
Symptoms include gait abnormalities, muscle stiffness, weakness, and bowel or bladder problems.
What does the long-term prognosis look like for someone with Hereditary Spastic Paraplegia?
The progression of HSP varies greatly from person to person; while some may need mobility aids, others continue walking throughout their lives.
What's the ratio of kids to adults affected by Hereditary Spastic Paraplegia?
HSP affects both children and adults, but exact ratios are not known due to the rarity of the condition. It often begins in childhood or adolescence, and progresses over time.
Hereditary Spastic Paraplegia (HSP) encompasses a diverse collection of genetic disorders characterized by progressive lower limb spasticity and weakness. These conditions are caused by mutations in specific genes, leading to the gradual degeneration of nerve fibers in the spinal cord that control leg movement. HSP affects approximately 1 in every 20,000 to 200,000 individuals worldwide, with symptoms typically appearing during childhood or adolescence.
HSP symptoms can vary from person to person, but there are some common signs to watch for. Here’s what you might notice:
| Age of Onset | Possible Symptoms |
|---|---|
| Childhood | Delayed walking, toe-walking, frequent tripping |
| Adolescence/Adulthood | Gradual leg weakness, stiffness, and gait changes |
If you notice any of these signs in your child, it’s best to talk to a doctor. They can help determine if it’s HSP and create a plan to manage symptoms.
