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CNTN4 is a gene that helps brain cells connect with each other during early development. Changes in this gene may be linked to some developmental conditions, like autism and intellectual disability.
How does CNTN4 affect my child's behavior?
CNTN4 variations may influence skills like communication and attention. It’s one piece in understanding your child’s unique abilities.
Is CNTN4 only related to developmental conditions?
While CNTN4 is often discussed in the context of conditions like autism and ADHD, it’s just one factor among many that influence brain function.
What are some practical tips for parents of children with CNTN4 variations?
Use visual aids to help with routines and consider skill-building apps for emotional regulation. Every child is different; tailor strategies to fit yours.
The CNTN4 gene, located on chromosome 3, encodes a protein called contactin-4. This protein is involved in forming and maintaining connections between neurons in the developing nervous system. Variations or deletions in the CNTN4 gene have been associated with an increased risk for neurodevelopmental disorders, such as autism spectrum disorder (ASD) and intellectual disability. Research suggests that alterations in CNTN4 may contribute to atypical brain connectivity and function in these conditions.
CNTN4 plays a crucial role in brain development and function. Here are some key ways this gene is used:
| Function | Description |
|---|---|
| Neuronal connections | CNTN4 helps guide the formation of connections between nerve cells during brain development. |
| Synaptic function | The protein encoded by CNTN4 is involved in the proper functioning of synapses, the communication points between neurons. |
| Axon guidance | CNTN4 assists in directing the growth and pathfinding of axons, the long nerve fibers that transmit signals. |
By understanding the role of CNTN4 in brain development, researchers can better understand how variations in this gene may contribute to neurodevelopmental differences and develop targeted support strategies for affected individuals.
This post was originally published on Sept. 17, 2023. It was updated on April 23, 2024.
