Fragile X syndrome is a genetic condition that affects brain development. It can cause learning difficulties, behavioral challenges, and certain physical features. Fragile X is the most common inherited cause of intellectual disability.
Fragile X syndrome is a genetic condition that affects brain development. It can cause learning difficulties, behavioral challenges, and certain physical features. Fragile X is the most common inherited cause of intellectual disability.
Can Fragile X syndrome be cured?
There is no cure for Fragile X syndrome, but doctors and therapists can help manage symptoms and improve skills with therapy, medication, and special education.
Is Fragile X syndrome hereditary?
Yes, Fragile X syndrome is caused by a change in a person’s genes and can be passed down through families.
How common is Fragile X syndrome?
Fragile X syndrome is considered a rare condition, but it is the most common inherited cause of intellectual disability. It affects about 1 in 4,000 boys and 1 in 8,000 girls.
Fragile X syndrome (FXS) is a genetic disorder characterized by mild to severe intellectual disability, behavioral and learning challenges, and various physical features such as an elongated face, large ears, and flat feet. FXS is caused by a mutation in the FMR1 gene on the X chromosome, leading to reduced or absent production of the fragile X mental retardation protein (FMRP). It is estimated to affect approximately 1 in 4,000 males and 1 in 8,000 females.
Children with Fragile X syndrome may exhibit a range of symptoms that vary in severity. Some common signs include:
| Intellectual disability | Ranging from mild to severe |
| Delayed speech and language | Expressive language often more affected |
| Behavioral challenges | Anxiety, ADHD, sensory sensitivities |
| Physical features | Long face, large ears, flat feet |
Symptoms can vary between individuals and may become more apparent as a child grows older. Girls with FXS often have milder symptoms than boys. Early recognition of symptoms allows for timely interventions and support.
This post was originally published on March 31, 2023. It was updated on May 24, 2024.
